New Hope for Most Severe Chronic Cases of Lyme Disease! Part One

Has anyone heard of Lumbrokinase? Well, if you haven’t, lumbrokinase is a group of six, novel proteolytic enzymes derived from the earthworm Lumbricus Rubellus, and it is slowly establishing itself as possibly the best and brightest new treatment for chronic Lyme sufferer.

I say “new treatment” because it is new information for me – generously supplied by a fellow “Lymie” Ted Patterson who has tried it and “feels better than he has in years”. The more I researched this enzyme, the more excited I have become.

First, lumbrokinase has been used successfully in China’s four top hospitals in nerve and infectious diseases since 1995 without any harmful side effects. Initially used for the potent ability to dissolve blood clots and vein thrombosis, it was soon discovered to improve the quality of blood in a number of ways that are still being discovered.

According to Allery Research Group, medical reports from leading researchers and doctors have further discovered the power of lumbrokinase to not only dissolve clots which obviously helps protect against heart disease and strokes, but also:

to lower fibrinogen levels in cancer patients, which is strongly associated in scientific studies with better outcomes, less metastasis, and slower growth of tumors;
to offer antiplatelet, anti-thrombotic and self-destructive cellular activity, remarkably regulating hypercoagulation; and most importantly for us,
to dissolve bacterial biofilms present in chronic infections in conditions like autism and Lyme disease, allowing antimicrobials and anti-bacterials as well as our own immune system to work effectively and quickly to destroy the colonies that hide behind the biofilms.

Biofilms have been recently discovered as one of the key biological roadblocks to curing many chronic diseases, especially (for our purposes) Lyme disease. It is a remarkable breakthrough, and it ultimately could have a huge effect on Lyme disease sufferers and possibly their life insurance quotes and policies because of a longer life expectancy among those infected.

Peta Cohen, M.S., R.D., is the founder of Total Life Center in Northern New Jersey, and has a Masters Degree in Clinical Nutrition, was recently interviewed by Allergy Research Group (read entire interview here), and offers these insights into biofilms:

“I do a tremendous amount of testing and assessing the children through urine and fecal analysis. What got me so interested in nattokinase and lumbrokinase was the concept of what a biofilm infection actually is. If you do a medline search on biofilms and platelet aggregation, fibrinogen, and fibrin, boom, it’s there right in your face.

“Bacteria build biofilms by first aggregating together, and then rapidly weaving this protective web or matrix around them. They build a polymeric matrix. It’s a sticky, gluey, mucus-y goop and it’s got fibrin in it to give it an intact structure. The bacteria recruit fibrinogen to create fibrin as part of that matrix. At that point they can shed their outer membrane, which has the proteins that serve as antigens and as a target of the missile of the immune system. They’re very protected. They’re very crafty in creating a way to survive and procreate and hide from the immune system.”

In neurological Lyme disease, the biofilm is believed to be constructed of actual bits and pieces of our myelin sheath which covers and protects our actual nerves that make up our central nervous system. So when the immune system calls for killer cells to destroy the invaders, our immune system can actually attack our central nervous system trying to break through the biofilm and destroy the infection which they cannot do.

So, as lumbrokinase dissolves this biofilm, we have hope that our killer cells, or in more critical cases where the immune system is no longer working effectively, antibiotics (pharmaceutical or herbal) will be able to destroy the infection and return us to health!

See product here.

Look for Part Two on “nattokinase”, and please comment if you have any experience to relate regarding lumbrokinase.

To read excerpts from LLD’s who are using lumbrokinase successfully, read:

Two Doctors Use Lumbrokinase to Help Conquer Lyme Disease

Jeanne

(2 comments):
May 7th, 2009 at 8:35 am

My LLMD just recommended this to me. I’m on nattokinase, which is really effective in lessening the hyper-coagulation. So much that the paramedics had to help me stop a kitchen knife cut to the finger last night. I’m looking forward to trying it.

Thank!

lymemama.wordpress.com

Jenna’s Lyme Blog « Betaine HCL Protocol:
May 18th, 2009 at 4:34 am

[...] Lumbrokinase [...]

KeHoeff

(1 comments):
May 28th, 2009 at 5:59 pm

hey this is a very interesting article!

(2 comments):
July 10th, 2009 at 10:36 pm

Yep. Got that it is lumbrokinase. . .I’m on natto and excited to try lumbro as well. Thanks for posting the article.

Bianca

(1 comments):
August 23rd, 2009 at 4:05 pm

Hi there, this sounds very promising as well as interesting. How is it done so any websites that are recommended? Is it injected, taken as a powder/pill, or a liquid? Or could I just go out and feed my poor hubby some earth worm dinner? Sorry, my funny bone tickled me – I know this is all no laughing matter but I still try to keep humor going…Thanks all!

Jenna Smith

(186 comments):
August 24th, 2009 at 1:46 pm

Hi Bianca -

No need to dig up worms…but I share your humor!

The enzymes are extracted from the worms and encapsulated so it means more capsules to take.

I am starting to feel a significant difference myself although it is hard to pinpoint the hero in the mix…my protocol is listed here: http://www.lymediseaseresource.com/Jennas_Treatment.html but I always remind people that everyone is unique and their cure not be the same necessarily…my sincere hope for your husbands full recovery!

Blessings,
Jenna

Debbie

(1 comments):
September 14th, 2009 at 1:43 pm

Grateful to have found this site. I swear that back in June when I Googled “lumbrokinase lyme” that NO hits came up.

Nattokinase didn’t work for me. The contrast between natto and lumbro is exponential.

Go, earthworms, go! My butt was severely kicked with Herxing when I added the (Boluoke brand) lumbrokinase to my system. It has taken these critters out of hiding and has made the herbs and supplements I’ve been on incredibly effective. So effective, in fact, that I’ve had to reduce the dosages on most of them. Halle-freakin’-lulia (they’re expensive). The current focus is to get me to a dosing schedule where I’m not taken out of life with Herxing. Still experimenting with how to “meter” it in. When I come out of the latest foray into Herxing hell, I will try the lumbrokinase and the “other goodies” for one day and take the rest of the week off.

Thanks for a forum for me to share a most positive response to the lumbro. I feel so exicited about feeling so crappy!

Blessings,
Debbie

(186 comments):
September 14th, 2009 at 3:46 pm

Hi Debbie -

Thanks for your comment! I am on all three so I’m not sure which gave me the herx – a really but I know just what you mean about feeling great about feeling crappy – it sounds insane to those who haven’t experienced it!

I sincerely hope you continue on your bumpy roller-coaster ride to complete health and ENERGY!! I promise to write more when I get over this latest big herx…but I love comments so thanks again -

Blessings,

Jenna

Steven Sponaugle

(8 comments):
September 16th, 2009 at 7:56 pm

Florida Detox and Wellness Institute has started using Nattokinase and Lumbrokinase, with some of our patients suffering from Lymes, Babesia, West Nile Virus, Migraine and Mycoplasma. Patients have noticed improvement the first or second day, with either supplement. Some who switched to Lumbrokinase, from Nattokinase, noticed additional improvement, compared to Nattokinase. These patients have had high fibrinogen, thrombin-antithrombin, C4A, C3A or Factor V Leiden. We have not noticed any adverse reaction so far. We are finding thrombin-antithrombin is often excessive, even when fibrinogen is below 310. If your PTT clotting time is fast (near 25 seconds) you might want to have your fibrinogen and thrombin-antithrombin tested.

The Vitamin C/glutathione IV is the kindest, gentlest, most effective Lymes, Babesia, Mycoplasma,West Nile Virus and Migraine treatment we have found so far, but Nattokinase and Lumbrokinase have definitely produced additional improvement, beyond the intravenous therapy.

Bromelain, 1000 milligrams daily, lowered elevated fibrinogen a couple hundred units, for some of our patients, but they did not feel any better.

Has anyone used Serrapeptase?

Steven Sponaugle
Research Director
Florida Detox and Wellness Center
http://www.floridadetox.com

(186 comments):
September 19th, 2009 at 12:27 pm

Hi Steven -

Thank you for your informative comment!

I have used Serrapeptase as it is included in Natto+, and I am amazed at the progress I am making…although its hard to determine which enzyme is working best!

I am pleased to have my research validated by you – it is one more step in the right direction!
Blessings,

(8 comments):
September 20th, 2009 at 4:51 pm

Thanks for your response and congratulations on the terrific blog you host.

We have not tried Serrapeptase yet, but probably will soon, since it appears to have an additional anti-inflammatory effect.

Mary Segalla

(2 comments):
October 18th, 2009 at 3:25 pm

This is such good information, I just took it to my LLMD who said take the Lumbrokinase, but he didn’t seem impressed with the Nattokinase. I have a question, though. At the end of this article, and the 3rd article in this series,you link to the “best” products to buy. But on your “Jenna’s treatment” page, I notice you link to different products from different companies. Can you please tell me which you prefer, use now, or something? I have spent hours trying to decide which to buy and reading many things and it’s gotten quite confusing! Thanks so much!
Mary

(186 comments):
October 18th, 2009 at 7:29 pm

Hi Mary -

Thanks for your comment! I must admit that there are times when I can’t afford the best brands…and that is just for now. I am in the Medicare donut hole (I’m not sure if you know the term but once Medicare has pays a certain amount, then you are liable for a big chunk of copay before the insurance kicks in again.) I am sorry to say that this illness has really crushed me and I am slowly recovering (FINALLY!)

If you have any more questions, please don’t hesitste to email – my Lyme fog still overcomes me…at time…

Thanks again for your comment, and please be well.

Blessing,
Jenna Smith

(8 comments):
October 18th, 2009 at 10:14 pm

Mary,

Our patients are obtaining good results with NOW Nattokinase and Allergy Research Group Lumbrokinase. At least two patients have felt more improvement with Lumbrokinase, although Nattokinase appears to have a longer half life. They have been taking 4 Nattokinase 100 mg capsules or 4 Lumbrokinase capsules daily. We are increasing one of our Babesia patients to 6 Lumbrokinase capsules daily after rechecking his Prothrombin time, PAI-1, INR, fibrinogen and plasminogen.

Many of our migraine and fibromyalgia patients also have elevated fibrinogen, or thrombin-antithrombin. One migraine patient also had elevated platelets, in addition to high fibrinogen.

We gave up trying to refer these patients to hematologists, after hematologists looked at their elevated fibrinogens, fast clotting times, high Lp(a),elevated Factor V or C3a/C4a and denied a need for anticoagulation. Seems hematologists are not interested, unless cancer or aplastic anemia are involved.

You can easily lose a month of anticoagulation benefit while you wait for a hematology appointment. A stroke or cardiac could also occur, while anticoagulation is stalled, waiting for a hematologist appointment.

Steven Sponaugle
Research Director, Florida Detox and Wellness Institute
http://www.foridadetox.com

(2 comments):
October 19th, 2009 at 5:35 pm

Thank you so much for this great information! I must say it’s killing us how much my being “sick” is costing. My lyme dr does not take insurance, and it’s several hundred dollars a month. i keep hoping I’ll get to the point I don’t need to go every month. Then you add all the supplements. And being unable to work. So saving money in any way with this helps alot!

Jenna I love your website, it is one of the few I frequently refer to.

Blessings in abundaance,
Mary

Mary

(2 comments):
October 20th, 2009 at 4:10 pm

Jenna, how much do you take of each, if I may ask? I ordered the Nattokinase + because it seemed cheaper in the end than to order it separate from the Serrap. Thanks

(186 comments):
October 24th, 2009 at 11:17 am

I’m sorry it has taken me so long to respond – I am dealing with moving from a 4 bedroom house to a small 2 bedroom apartment…I sleep more than I pack!!

Anyways, to answer your question (in case I haven’t already) I take one Lumbrokinase and one – two Nanno+ 3 times a day depending upon my finances – I’m sure you know how that goes!

Hope you’re feeling better – remember, it takes time for the biofilms to dissolve and then the herxing will come so be prepared to feel really bad at some point and then take 2 Sarsaparilla 3 times a day. It is the best supplement for herxing!

(2 comments):
October 27th, 2009 at 8:12 am

Jenna good luck with your move from a big home to a small apartment! I can’t imagine moving with the fatigue and weakness, I hope you have good help! Thanks for letting me know how much you take of this. I am not sure how long I have had lyme, could be 30+ yrs, I grew up in CT and lived my 18th summer in a pasture with my horse. Ended up at the end of the summer in the hospital with high fever and complete exhaustion, weakness to the point of being unable to stand and swollen liver. That was 1975. They never figured out what was wrong with me and I got “better”, but my entire adult life have had weird unexplainable ailments, until this last year when I totally crashed and was diagnosed with MS. Have also lived in KY, VA, ME, FL and MO, and gotten tick bites in all those places! So I might just have a huge mix of cross cultural infection! Thank God for Igenex, that finally gave us a double positive, following at least 12 tests that were negative from CDC labs. Anyway, sorry for rambling, and be blessed!

(186 comments):
October 27th, 2009 at 10:40 am

I find stories like yours (and my very similar history) to be frightening beyond belief…and Obama calls the swine flu a national emergency…Lyme makes the swine flu seem like a pimple!!

Sorry for the dark mood.

(8 comments):
October 27th, 2009 at 12:05 pm

Jernna.

Great metaphor.

John Holmes

(1 comments):
October 31st, 2009 at 11:27 am

I’ve recently been diagnosed with Lyme and I am very interested in this protocol. I’m currently in my first week and trying both Lumbrokinase (Doctors Best Brand) and Nattokinase+. I was wondering – when using different enzymes, can I take them both at the same time or should I take them separately in order to avoid absorption issues?

I’m also currently using Samento as an natural antibiotic.

Many thanks

Adrian

(186 comments):
November 4th, 2009 at 1:42 pm

Hi Adrian -
The enzymes work together so don’t worry about absorption issues – just follow the instructions on the bottle. Just a side note, if you eventually can only afford one – take the Lumbrokinase but the three are the best and work together with other herbs and vitamins you are taking.

God bless,
Jenna

Christian Hyzer

(1 comments):
October 23rd, 2010 at 6:35 pm

This is probably one of the best articles I have located on this topic. I would like to know if you have you looked into the other side of the subject of natural health? To be candid, I think a solid argument could be made either way, but let me know if you know of more articles or sources on the Web that back up what you are discussing.

Lionel Welding

(1 comments):
October 29th, 2010 at 7:49 am

Some very nice material you presented here, some I agree with a few less with the rest.

Fred

(1 comments):
November 29th, 2010 at 8:46 pm

hello Jenna; my x-wife, who is with me now in Iowa, was diagnosed with Lyme disease 2 yrs. ago. No telling how long she has had it. It could be over 10 yrs now. We were married when i noticed ticks and a rash. which was over ten yrs ago. Not knowing anything about Lyme and the doctors didn’t help. she was treated for so many different problems and none of them where ever cured! She was on a two yrs worth of anti-biotics. she got better but it was a rollercoaster of back and forth. A few months ago I started giving her cats claw and it seems she is getting better without all the herxing. I am over whelmed with it all. Lumbrokinase sounds good but I just can’t figure out if it is the right one to use with the cats claw or shoud I use samento? What should I do, who should I ask, where should I go to find out???????? Thank you. I do not want to put you on the spot, but can you help me? Fred

(186 comments):
December 6th, 2010 at 2:09 pm

Hi Fred -
I share in the overwhelming confusion that can paralyze even the most action-oriented person.

The truth is that we each have a unique case of Lyme based upon our underlying health conditions when we contract it.

You are not putting me on the spot, and there is nothing I would enjoy more than to steer you in the right direction. If she was on 2 years of abx then she must have had a Lyme-literate doctor who is important when you get in a bind. I take Cat’s Claw because it has verifiably raised my CD-57 but it was not enough on its own and now I am on IVIG infusions – basically rebuilding my immune system up from ground zero.

For your x-wife, I would recommend continued Cats Claw, Transfer Factor (http://www.dpbolvw.net/click-3278140-10374326target=_blank?url=http://www.houseofnutrition.com/admelatrfaba.html), Gold 360 (http://tinyurl.com/Gold360MB), and ApplePoly (http://tinyurl.com/applepolyMB) for building up the immune system; and then Himalayan salt caps (http://amzn.to/himsalt) and teasel drops (ladybarbara.net) to fight the infection…That is what I would do but I am not a doctor. Obviously you want to be very careful about allergies…I wish you every blessing and patience to find peace in this indescribable horror. You are a good man to return to your exwife in her time of need…I see so many men and women deserted by their spouses due to Lyme. God bless you!

Christa G.

(1 comments):
March 29th, 2011 at 5:16 pm

Hi, thank you so much for this article! I’m only 15 years old but got diagnosed with Lyme disease when I was in 6th grade. At first I got really sick (migraine for a full 7 days + throwing up + fever) then kind of bounced back but still with joint pain and headaches, etc. I am at a point right now where I miss at least one day of school a week because of not feeling well and being weak which stresses me beyond belief, and I am just trying to (and have been) find something that will at least help me a LITTLE bit. I have changed my diet and lifestyle not too long ago (eating healthy and exercising regularly) which helps a slight bit, but I still seem to have no energy especially when I get home from school. On top of that, I get a headache every day (not exaggerating) and I’m not sure why. A close friend of mine told me about a few different medicines to try (Lumbrokinase, Serrapeptase, and Venus Fly Trap Extract) but my mom doesn’t want to purchase any of them yet without knowing they’re capabilities and what they do; so I’m doing some research and I came across this! I was wondering if you could just give me some insight as to whether or not you think it would work for me, if I should try it, …I’m just looking for an opinion besides my own. Thank you so much for taking the time to read this! God Bless

Steve Sponaugle

(1 comments):
June 17th, 2011 at 10:44 am

Disclaimer

I am not a Physician and this post should not be considered a substitute for medical examination, testing, diagnosis or treatment.

Nattokinase is safer than Lumbrokinase or Serrapeptase, since it’s anticlotting effects are moderated by Plasminogen feedback pathways. A Nattokinase dose of 2 caps, three times daily, can provide around the clock coverage.

Migraine sufferers frequently have highly elevated Thrombin/Antithrombin levels, at least intermittently. Lumbrokinase can dissolve the excess Thrombin and is especially helpful for patients with migraines, although it has a much shorter half life of about 2 hours. Lumbrokinase is usually more expensive than Nattokinase or Serrapeptase.

Serrapeptase is the most powerful anticlotting enzyme and is especially helpul for scleroderma and can also dissolve Lyme disease biofilm more effectively, than Nattokinase. Serrapeptase doses over 80,000 units for more than a month, have caused breathing problems in some situations. Serrapeptase dosages of 40,000 units daily, seldom seem to cause excess bleeding.

(186 comments):
June 18th, 2011 at 7:07 am

Steve,
Thanks for the great info! Very important –
Blessings,
Jenna

Kim

(4 comments):
August 25th, 2011 at 5:24 pm

Thank you for your site (I suppose you’re tired of hearing that) and all you are doing. I started the Buhner protocol before I had the book because I was suffering too much with a single headache that has lasted since March of 2007. Being on Abx for the CDC’s recommended amount of time until I was re-tested and still positive for Lyme, my Doctor is more confident to keep me on Doxy for the last few years just to maintain some form of life in me. After just 2 days on Cats Claw, my “brain felt cool”. I knew we were on to something. I’ve added herbs as money permits and came across (somewhere) about the Lumbro/Serra/Natto information, and now, your blog. If I understand what You are doing, it’s 1-2 Lumbro 3x/day (my bottle says 40mg/600,000IU per tab.) 1-2 Natto 3x/day on an empty Stomach (my bottle says 150mg/3,000FU) and Serrapeptidase/Serrapeptase 40,000SPU/day (mine says 120,000U so it’d be every 3rd day or so, in your experience). For Herx you said you use 2 3x/day of Sarsparilla. You mentioned IVIG infusions would you care to expand upon what is involved there?

(186 comments):
August 26th, 2011 at 7:19 am

Hi Kim – No, I never tire of encouragement from readers…it is what keeps me going! I am so glad I could help in some way. The info I have posted on the biofilm busters evolved as new information was released and if you look under protocols on the home website (not the blog) you will see the exact protocol I use now which I have to pulse because it is so strong. The brand of product is important and I make very specific recomendations on the website (www.LymeDiseaseResource.com).

I wrote 3 posts on the IVIG infusions – I’m not sure what you would like expanded on – if you could be more specific that would help. The infusions are prescribed by your doctor after they have evaluated your immune system with a blood test and found your immune system diminished, so the first thing to do is get your doctor to evaluate your immune system.

I am happy to hear that the Cat’s Claw had an immediate impact…another “super”supplement is GABA – I started with 750 mg caps as needed – especially helpful at night to help sleep through the pain.

Jim Price

(1 comments):
September 11th, 2011 at 1:28 am

I was hit hard with lyme 5 years ago, no ins, and don’t trust the medical field at all. Did some research on line and found http://www.lymephotos.com. Followed the protocol and within a few weeks i was able to focus/concentrate again and some of the fatigue was gone, the pain wasn’t as bad and after two years the herxing stopped and i dropped down to one dose a day. Still have kinks in the neck sometimes and ringing in the ears all the time, but no more back,joint,lower jaw pain or heart block and no muscle twitches and i haven’t been lost or disoriented in about 4 years now. Anyone tired of giving money to doctors and drug companies should probably check it out. It’s only sea salt and vitamin c and it works for me.

(4 comments):
September 18th, 2011 at 3:18 am

Just be aware, California does not allow it to be shipped into the state. Took it while in other places and felt better, but am taking serrapeptase and nattokinase until California gets with the program.

Building More Killer Cells For Chronic Lyme Disease | About Lyme Disease:
November 28th, 2011 at 7:07 am

[...] New Hope for Most Severe Chronic Cases of Lyme Disease! Part One [...]

New Hope for Most Severe Chronic Cases of Lyme Disease! Part Three | About Lyme Disease:
December 1st, 2011 at 9:16 am

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New Hope for Most Severe Chronic Cases of Lyme Disease! Part One

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